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For safe and effective use of this medicine, do not take more of it, do not take it more often, and do not take it for a longer time than ordered by your doctor. Nabumetone is used to reduce pain, swelling, and joint stiffness from arthritis. Taking too much of this medicine. Find user ratings and reviews for nabumetone (bulk) on webmd including side effects and. Diarrhea (14%), dyspepsia (13%), abdominal pain (12%) common (1% to 10%):.